Orchard Therapeutics plc (ORTX) NASDAQ

16.70

+0.05(+0.30%)

Updated at January 23, 2024 04:00PM

Currency In USD

Orchard Therapeutics plc

Address

108 Cannon Street

London, EC4N 6EU

United Kingdom of Great Britain and Northern Ireland (the)

Phone

44 20 3 808 8286

Sector

Healthcare

Industry

Biotechnology

Employees

166

First IPO Date

October 31, 2018

Key Executives

NameTitlePayYear Born
Hubert Baburaj GasparChief Executive Officer, Member of Scientific Advisory Board & Executive Director901,4251963
Frank E. ThomasPresident & Chief Operating Officer763,9531969
Leslie MeltzerChief Medical Officer0N/A
Nicoletta LoggiaChief Technical Officer0N/A
Braden ParkerChief Commercial Officer0N/A
John CerioChief Human Resource Officer0N/A
Robin KenselaarSenior Vice President & GM of EMEA Commercial Operations0N/A
Renee T. LeckHead of Investor Relations0N/A
Benjamin NavonDirector of Corporation Communications0N/A
Fulvio MavilioChief Scientific Officer0N/A

Description

Orchard Therapeutics plc, a biopharmaceutical company, develops gene therapies for serious and life-threatening rare diseases in the United Kingdom, European Union, and the United States. The company's gene therapy approach seeks to transform a patient's hematopoietic stem cells into a gene-modified cellular drug product to treat the patient's disease through a single administration. It provides Strimvelis, a gammaretroviral-based product for the treatment of adenosine deaminase-severe combined immunodeficiency (ADA-SCID). The company's clinical development products comprise OTL-101 for the treatment of ADA-SCID; OTL-200 to treat metachromatic leukodystrophy; OTL-103 for the treatment of Wiskott-Aldrich syndrome; OTL-102 for X-linked chronic granulomatous disease; and OTL-300 for transfusion-dependent beta-thalassemia. Its preclinical programs include OTL-203 for mucopolysaccharidosis type I, OTL-201 for mucopolysaccharidosis type MPS-IIIA, and OTL-202 for mucopolysaccharidosis type IIIB. It has a strategic collaboration agreement with Pharming Group N.V. for research, development, manufacturing, and commercialization of OTL-105, an investigational ex vivo autologous hematopoietic stem cell gene therapy for the treatment of hereditary angioedema. The company was formerly known as Orchard Rx Limited. Orchard Therapeutics plc was founded in 2015 and is headquartered in London, the United Kingdom.