Sangamo Therapeutics, Inc. (0R1D.L) LSE

Currency In USD

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Sangamo Therapeutics, Inc.

Address

501 Canal Blvd

Richmond, CA 94005

United States of America (the)

Phone

510 970 6000

Sector

Healthcare

Industry

Biotechnology

Employees

183

First IPO Date

November 07, 2014

Key Executives

NameTitlePayYear Born
Alexander D. Macrae Ch.B MRCPChief Executive Officer, President & Director930,2551963
Scott WilloughbySenior Vice President, Chief Legal Officer & Corporate Secretary569,6511975
Nathalie Dubois-StringfellowSenior Vice President & Chief Development Officer585,2241962
Gregory DavisHead of Research & Technology01970
Stephanie J. SeilerVice President and Head of Business Development & Alliance Management0N/A
Phillip RamseyChief Technical Officer0N/A
Louise WilkieHead of Global Corporate Communications & Investor Relations0N/A
Nikunj JainInterim CFO and Principal Financial & Accounting Officer01980
David OjalaScientist II - Discovery & Translational Research0N/A
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Description

Sangamo Therapeutics, Inc. is a biotechnology firm currently in the clinical development phase, dedicated to converting scientific discoveries into groundbreaking genomic therapies. These therapies aim to significantly improve patients' lives, leveraging advanced platform technologies including gene therapy, cell therapy, genome editing, and genome regulation. Central to its operations is the zinc finger protein (ZFP) technology platform. This platform facilitates the creation of zinc finger nucleases, specialized proteins adept at altering DNA sequences by either inserting or deactivating particular genes. Additionally, it produces ZFP transcription factors, which are proteins utilized to either boost or diminish gene expression. The company's developmental pipeline includes several promising treatments: SB-525, currently undergoing Phase III AFFINE clinical trials for hemophilia A; ST-920, a gene therapy in Phase I/II STAAR clinical trials targeting Fabry disease; and SAR445136, a cell therapy undergoing Phase I/II PRECIZN-1 clinical trials for sickle cell disease. Further candidates in development are TX200, a chimeric antigen receptor designed to address HLA-A2 mismatched kidney transplant rejection; KITE-037, a cell therapy for various cancers; ST-501 for tauopathies; and ST-502, intended for synucleinopathies such as Parkinson's disease and other neuromuscular conditions. Sangamo maintains numerous collaborative and strategic alliances with prominent entities such as Biogen MA, Inc., Kite Pharma, Inc., Pfizer Inc., Sanofi S.A., Novartis Institutes for BioMedical Research, Inc., Shire International GmbH, Dow AgroSciences LLC, Sigma-Aldrich Corporation, Genentech, Inc., Open Monoclonal Technology, Inc., F. Hoffmann-La Roche Ltd, Hoffmann-La Roche Inc., and the California Institute for Regenerative Medicine. Originally incorporated in 1995, the company operated under the name Sangamo BioSciences, Inc. until its renaming to Sangamo Therapeutics, Inc. in January 2017. Its corporate headquarters are located in Brisbane, California.

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