Ionis Pharmaceuticals, Inc. (IONS) NASDAQ

Currency In USD

IONS Historical Return

If you invested $1000 in Ionis Pharmaceuticals, Inc. (IONS) 10 years ago, it would be worth $578.54 as of November 12, 2026, based on a reinvested dividends scenario. Over the same period, a $1000 investment made 5 years ago would be worth $840.47, while $1000 invested 1 year ago would be worth $378.08. This corresponds to total returns of -42.15%, -15.95%, -62.19%, respectively, with annualized returns of -5.33%, -3.41%, -62.19%.

Custom investment amounts or purchase dates can also be explored using the Stoculator calculator. Past performance does not guarantee future results.

IONS Historical Data

Date Range:

Date	Open	Close	Adj Close	High	Low	Volume
November 11, 2026	28.59	28.33	28.33	29.42	28.25	6.46M
November 10, 2026	30.31	28.19	28.19	30.49	27.77	10.68M
November 09, 2026	32.15	31	31	32.58	27.75	19.49M
November 06, 2026	39.02	39.42	39.42	39.97	38.52	2.88M
November 05, 2026	40.31	38.8	38.8	40.5	38.31	2.97M
November 04, 2026	41.38	40.15	40.15	41.53	39.33	3.89M
November 03, 2026	41.35	40.42	40.42	41.83	40.26	3.95M
November 02, 2026	43.66	41.24	41.24	43.91	41.19	2.55M
October 30, 2026	44.69	43.52	43.52	45.12	43.27	1.52M
October 29, 2026	45.57	44.39	44.39	45.84	44.04	1.81M
October 28, 2026	43.16	44.9	44.9	44.95	43.05	1.72M
October 27, 2026	43.23	43.96	43.96	44.1	43.02	2.38M
October 26, 2026	43	43.42	43.42	43.92	42.76	3.2M
October 23, 2026	43.8	42.93	42.93	43.8	42.58	3.01M
October 22, 2026	45.02	43.91	43.91	45.15	43.41	5.01M
October 21, 2026	45.55	44.27	44.27	45.76	44.26	2.27M
October 20, 2026	44.45	45.4	45.4	45.48	44.01	2.49M
October 19, 2026	43.33	44.38	44.38	44.54	43	2.84M
October 16, 2026	44.53	42.94	42.94	44.65	42.8	1.67M
October 15, 2026	43.58	44.12	44.12	44.71	43.42	2.48M
October 14, 2026	42.22	42.7	42.7	43.47	42.08	2.03M
October 13, 2026	43.55	42.38	42.38	43.58	42.36	2.98M
October 12, 2026	45.37	43.67	43.67	45.46	43.62	1.91M
October 09, 2026	43.21	45.28	45.28	45.72	43.12	4.86M
October 08, 2026	43.76	43.3	43.3	44.19	42.79	3.35M
October 07, 2026	43.75	44.16	44.16	44.26	43.53	2.7M
October 06, 2026	44.19	44	44	44.67	43.17	2.19M
October 05, 2026	43.75	43.5	43.5	43.96	42.63	2.87M
October 02, 2026	44.17	43.54	43.54	44.17	43.24	2.31M
October 01, 2026	44.63	44	44	45.95	43.96	2.03M
September 30, 2026	46.07	44.65	44.65	46.25	44.6	2.53M
September 29, 2026	45.53	45.89	45.89	46.46	45.39	3.71M
September 28, 2026	44.56	45.57	45.57	46.95	44.06	3.55M
September 25, 2026	44.25	44.5	44.5	45.28	43.62	6.14M
September 24, 2026	43.77	43.81	43.81	44.6	43.25	5.49M
September 23, 2026	46.23	43.93	43.93	46.41	43.01	3.52M
September 22, 2026	44.96	45.75	45.75	46.13	44.44	4.15M
September 21, 2026	44.95	44.9	44.9	45.25	44.2	4.34M
September 18, 2026	46.75	44.44	44.44	46.75	44.27	7.32M
September 17, 2026	46.68	46.75	46.75	47.42	45.75	4.02M
September 16, 2026	47.38	44.84	44.84	47.59	44.66	7.63M
September 15, 2026	51.37	47.25	47.25	51.37	46.72	6.75M
September 11, 2026	55.94	54.21	54.21	56.16	54.16	2.15M
September 10, 2026	55.75	55.65	55.65	55.77	54.91	2.94M
September 09, 2026	56.38	56.02	56.02	56.96	55.7	3M
September 08, 2026	52.15	56.71	56.71	57.43	52.15	9.1M
September 04, 2026	58.36	58.09	58.09	58.96	57.78	2.22M
September 03, 2026	60.42	58.13	58.13	60.42	57.47	4.26M
September 02, 2026	60.25	61.33	61.33	61.77	59.78	1.83M
September 01, 2026	60.37	59.88	59.88	60.99	59.78	1.87M
August 31, 2026	61.07	60.36	60.36	61.07	59.7	2.02M
August 28, 2026	60.62	61.05	61.05	61.69	60.35	1.85M
August 27, 2026	63.48	62.43	62.43	63.48	62.34	1.62M
August 26, 2026	63.5	63.36	63.36	63.55	62.44	2.15M
August 25, 2026	62.53	63.57	63.57	64.19	62.19	2.43M
August 24, 2026	60.54	62.04	62.04	62.07	59.7	2.21M
August 21, 2026	59.64	59.74	59.74	60.92	59.06	2.72M
August 20, 2026	60.03	58.76	58.76	60.41	58.6	2.12M
August 19, 2026	60.11	60.8	60.8	61.36	59.61	3.13M
August 18, 2026	58.41	59.62	59.62	60.19	58.02	3.19M