Karyopharm Therapeutics Inc. (KPTI) NASDAQ

Currency In USD

KPTI Historical Return

If you invested $1000 in Karyopharm Therapeutics Inc. (KPTI) 10 years ago, it would be worth $16.86 as of August 22, 2026, based on a reinvested dividends scenario. Over the same period, a $1000 investment made 5 years ago would be worth $25.27, while $1000 invested 1 year ago would be worth $311.11. This corresponds to total returns of -98.31%, -97.47%, -68.89%, respectively, with annualized returns of -33.51%, -52.08%, -68.89%.

Custom investment amounts or purchase dates can also be explored using the Stoculator calculator. Past performance does not guarantee future results.

KPTI Historical Data

Date Range:

Date	Open	Close	Adj Close	High	Low	Volume
August 21, 2026	1.85	1.96	1.96	1.97	1.82	873,614
August 20, 2026	2	1.82	1.82	2	1.82	859,990
August 19, 2026	1.94	2	2	2.01	1.94	0
August 18, 2026	1.88	1.93	1.93	1.96	1.82	0
August 17, 2026	2.02	1.81	1.81	2.03	1.79	1.39M
August 14, 2026	1.97	2.02	2.02	2.06	1.97	875,063
August 13, 2026	2.07	1.99	1.99	2.09	1.92	0
August 12, 2026	2.1	2.03	2.03	2.15	2	0
August 11, 2026	1.93	2.1	2.1	2.1	1.93	0
August 10, 2026	2.14	1.96	1.96	2.18	1.92	1.79M
August 07, 2026	1.98	2.12	2.12	2.12	1.91	0
August 06, 2026	1.88	1.95	1.95	2.01	1.88	1.18M
August 05, 2026	1.94	1.91	1.91	2.06	1.88	2.36M
August 04, 2026	2	1.96	1.96	2.11	1.94	3.77M
August 03, 2026	1.94	1.97	1.97	2.05	1.8	4.49M
July 31, 2026	2.19	1.92	1.92	2.43	1.8	22.14M
July 30, 2026	6.98	7.01	7.01	7.09	6.56	2.61M
July 29, 2026	7.04	6.86	6.86	7.47	6.73	436,849
July 28, 2026	7.1	7.09	7.09	7.14	6.75	531,284
July 27, 2026	7.45	7.09	7.09	7.84	7.02	527,466
July 23, 2026	7.14	7.09	7.09	7.19	6.75	680,124
July 22, 2026	7.92	7.18	7.18	8.02	7.05	713,626
July 21, 2026	7.49	7.86	7.86	8.27	7.46	938,741
July 20, 2026	9.4	7.47	7.47	9.45	6.49	2.33M
July 17, 2026	9.35	9.51	9.51	9.59	9.31	187,657
July 16, 2026	9.55	9.38	9.38	9.84	9.36	236,381
July 15, 2026	9.84	9.53	9.53	9.84	9.38	315,473
July 14, 2026	10.07	10.01	10.01	10.17	9.82	481,544
July 13, 2026	10.19	10.05	10.05	10.3	9.71	420,897
July 10, 2026	10.3	10.34	10.34	10.59	9.88	320,236
July 09, 2026	10.76	10.2	10.2	10.76	10.09	281,099
July 08, 2026	10.02	10.67	10.67	10.86	9.91	737,175
July 07, 2026	9.58	10.05	10.05	10.05	9.29	249,515
July 06, 2026	9.6	9.62	9.62	9.77	9.2	288,088
July 02, 2026	9.7	9.6	9.6	9.96	9.45	317,737
July 01, 2026	9.68	9.55	9.55	9.85	9.34	308,441
June 30, 2026	10.11	9.77	9.77	10.48	9.71	600,345
June 29, 2026	10.16	10.09	10.09	10.44	9.64	496,986
June 26, 2026	9.45	10.21	10.21	10.25	9.43	3.22M
June 25, 2026	9.08	9.46	9.46	9.65	9.01	440,522
June 24, 2026	9.63	9.12	9.12	10.09	9.02	351,859
June 23, 2026	8.89	9.65	9.65	9.7	8.78	711,992
June 22, 2026	9.1	9	9	9.23	8.85	356,259
June 18, 2026	9.6	9.02	9.02	9.74	8.9	491,887
June 17, 2026	9.2	9.4	9.4	9.83	9.06	283,580
June 16, 2026	9.64	9.1	9.1	9.64	9	321,903
June 15, 2026	9.65	9.64	9.64	9.8	9.37	172,427
June 12, 2026	9.1	9.5	9.5	10.22	9.04	564,583
June 11, 2026	9.11	9	9	9.24	8.96	200,245
June 10, 2026	8.67	9.11	9.11	9.34	8.58	284,674
June 09, 2026	8.68	8.69	8.69	9	8.43	324,139
June 08, 2026	9.18	8.5	8.5	9.44	8.43	260,159
June 05, 2026	9.04	9.08	9.08	9.23	8.85	0
June 04, 2026	9	9.07	9.07	9.39	8.84	218,856
June 03, 2026	9.08	9	9	9.09	8.48	499,676
June 02, 2026	9.81	9.23	9.23	9.82	8.5	583,771
June 01, 2026	9.28	9.82	9.82	9.88	8.99	330,029
May 29, 2026	9.12	9.1	9.1	9.46	8.94	290,708
May 28, 2026	8.98	9.11	9.11	9.25	8.72	179,211
May 27, 2026	8.99	8.98	8.98	9.98	8.74	624,426