Karyopharm Therapeutics Inc. (KPTI) NASDAQ
Currency In USD
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KPTI Historical Return
If you invested $1000 in Karyopharm Therapeutics Inc. (KPTI) 10 years ago, it would be worth $3.34 as of October 22, 2026, based on a reinvested dividends scenario. Over the same period, a $1000 investment made 5 years ago would be worth $5.37, while $1000 invested 1 year ago would be worth $69.12. This corresponds to total returns of -99.67%, -99.46%, -93.09%, respectively, with annualized returns of -43.46%, -64.83%, -93.09%.
Custom investment amounts or purchase dates can also be explored using the Stoculator calculator. Past performance does not guarantee future results.
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KPTI Historical Data
Date Range:
| Date | Open | Close | Adj Close | High | Low | Volume |
|---|---|---|---|---|---|---|
| October 21, 2026 | 0.36 | 0.42 | 0.42 | 0.43 | 0.36 | 1.55M |
| October 20, 2026 | 0.34 | 0.36 | 0.36 | 0.39 | 0.34 | 761,529 |
| October 19, 2026 | 0.4 | 0.35 | 0.35 | 0.4 | 0.33 | 1.25M |
| October 16, 2026 | 0.35 | 0.39 | 0.39 | 0.4 | 0.33 | 2.69M |
| October 15, 2026 | 0.31 | 0.35 | 0.35 | 0.35 | 0.31 | 1.32M |
| October 14, 2026 | 0.41 | 0.32 | 0.32 | 0.43 | 0.32 | 1.95M |
| October 13, 2026 | 0.49 | 0.43 | 0.43 | 0.5 | 0.4 | 1.75M |
| October 12, 2026 | 0.59 | 0.51 | 0.51 | 0.6 | 0.5 | 892,658 |
| October 09, 2026 | 0.6 | 0.61 | 0.61 | 0.63 | 0.57 | 962,002 |
| October 08, 2026 | 0.63 | 0.6 | 0.6 | 0.64 | 0.6 | 870,224 |
| October 07, 2026 | 0.65 | 0.65 | 0.65 | 0.69 | 0.63 | 737,955 |
| October 06, 2026 | 0.69 | 0.65 | 0.65 | 0.72 | 0.64 | 1.18M |
| October 05, 2026 | 0.8 | 0.67 | 0.67 | 0.8 | 0.63 | 1.98M |
| October 02, 2026 | 0.86 | 0.8 | 0.8 | 0.89 | 0.75 | 2.34M |
| October 01, 2026 | 1.19 | 0.87 | 0.87 | 1.2 | 0.85 | 2.63M |
| September 30, 2026 | 1.26 | 1.22 | 1.22 | 1.27 | 1.18 | 1.75M |
| September 29, 2026 | 1.62 | 1.21 | 1.21 | 1.63 | 1.2 | 1.86M |
| September 28, 2026 | 1.59 | 1.62 | 1.62 | 1.66 | 1.54 | 326,527 |
| September 25, 2026 | 1.73 | 1.62 | 1.62 | 1.77 | 1.57 | 1.47M |
| September 24, 2026 | 1.73 | 1.73 | 1.73 | 1.77 | 1.71 | 677,241 |
| September 23, 2026 | 1.81 | 1.75 | 1.75 | 1.84 | 1.66 | 957,447 |
| September 22, 2026 | 1.86 | 1.82 | 1.82 | 1.9 | 1.78 | 986,716 |
| September 21, 2026 | 1.81 | 1.86 | 1.86 | 1.92 | 1.79 | 1.62M |
| September 18, 2026 | 1.77 | 1.88 | 1.88 | 1.89 | 1.67 | 1.9M |
| September 17, 2026 | 1.75 | 1.79 | 1.79 | 1.85 | 1.66 | 1.09M |
| September 16, 2026 | 1.54 | 1.7 | 1.7 | 1.72 | 1.54 | 1.35M |
| September 15, 2026 | 1.59 | 1.54 | 1.54 | 1.7 | 1.53 | 1.33M |
| September 11, 2026 | 1.5 | 1.61 | 1.61 | 1.61 | 1.24 | 6.73M |
| September 10, 2026 | 1.68 | 1.62 | 1.62 | 1.68 | 1.6 | 798,386 |
| September 09, 2026 | 1.72 | 1.69 | 1.69 | 1.75 | 1.65 | 771,858 |
| September 08, 2026 | 1.77 | 1.72 | 1.72 | 1.79 | 1.7 | 1.01M |
| September 04, 2026 | 1.77 | 1.79 | 1.79 | 1.84 | 1.76 | 577,292 |
| September 03, 2026 | 1.78 | 1.77 | 1.77 | 1.81 | 1.72 | 0 |
| September 02, 2026 | 1.9 | 1.79 | 1.79 | 1.94 | 1.73 | 1.3M |
| September 01, 2026 | 2.02 | 1.85 | 1.85 | 2.07 | 1.84 | 1.6M |
| August 31, 2026 | 1.91 | 2.06 | 2.06 | 2.14 | 1.79 | 2.03M |
| August 28, 2026 | 1.98 | 1.87 | 1.87 | 1.99 | 1.86 | 823,206 |
| August 27, 2026 | 1.95 | 1.94 | 1.94 | 2.06 | 1.94 | 1.1M |
| August 26, 2026 | 1.92 | 1.96 | 1.96 | 1.99 | 1.86 | 753,601 |
| August 25, 2026 | 1.87 | 1.92 | 1.92 | 1.92 | 1.87 | 0 |
| August 24, 2026 | 1.95 | 1.86 | 1.86 | 1.96 | 1.83 | 840,490 |
| August 21, 2026 | 1.85 | 1.96 | 1.96 | 1.97 | 1.82 | 873,614 |
| August 20, 2026 | 2 | 1.82 | 1.82 | 2 | 1.82 | 859,990 |
| August 19, 2026 | 1.94 | 2 | 2 | 2.01 | 1.94 | 0 |
| August 18, 2026 | 1.88 | 1.93 | 1.93 | 1.96 | 1.82 | 0 |
| August 17, 2026 | 2.02 | 1.81 | 1.81 | 2.03 | 1.79 | 1.39M |
| August 14, 2026 | 1.97 | 2.02 | 2.02 | 2.06 | 1.97 | 875,063 |
| August 13, 2026 | 2.07 | 1.99 | 1.99 | 2.09 | 1.92 | 0 |
| August 12, 2026 | 2.1 | 2.03 | 2.03 | 2.15 | 2 | 0 |
| August 11, 2026 | 1.93 | 2.1 | 2.1 | 2.1 | 1.93 | 0 |
| August 10, 2026 | 2.14 | 1.96 | 1.96 | 2.18 | 1.92 | 1.79M |
| August 07, 2026 | 1.98 | 2.12 | 2.12 | 2.12 | 1.91 | 0 |
| August 06, 2026 | 1.88 | 1.95 | 1.95 | 2.01 | 1.88 | 1.18M |
| August 05, 2026 | 1.94 | 1.91 | 1.91 | 2.06 | 1.88 | 2.36M |
| August 04, 2026 | 2 | 1.96 | 1.96 | 2.11 | 1.94 | 3.77M |
| August 03, 2026 | 1.94 | 1.97 | 1.97 | 2.05 | 1.8 | 4.49M |
| July 31, 2026 | 2.19 | 1.92 | 1.92 | 2.43 | 1.8 | 22.14M |
| July 30, 2026 | 6.98 | 7.01 | 7.01 | 7.09 | 6.56 | 2.61M |
| July 29, 2026 | 7.04 | 6.86 | 6.86 | 7.47 | 6.73 | 436,849 |
| July 28, 2026 | 7.1 | 7.09 | 7.09 | 7.14 | 6.75 | 531,284 |
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