Karyopharm Therapeutics Inc. (KPTI) NASDAQ

Currency In USD

KPTI Historical Return

If you invested $1000 in Karyopharm Therapeutics Inc. (KPTI) 10 years ago, it would be worth $0.12 as of November 11, 2026, based on a reinvested dividends scenario. Over the same period, a $1000 investment made 5 years ago would be worth $0.14, while $1000 invested 1 year ago would be worth $3.19. This corresponds to total returns of -99.99%, -99.99%, -99.68%, respectively, with annualized returns of -59.54%, -83.06%, -99.68%.

Custom investment amounts or purchase dates can also be explored using the Stoculator calculator. Past performance does not guarantee future results.

KPTI Historical Data

Date Range:

Date	Open	Close	Adj Close	High	Low	Volume
November 10, 2026	0.03	0.02	0.02	0.03	0.02	21.07M
November 09, 2026	0.04	0.04	0.04	0.04	0.04	20.62M
November 06, 2026	0.05	0.05	0.05	0.05	0.04	100.39M
November 05, 2026	0.05	0.06	0.06	0.06	0.05	13.3M
November 04, 2026	0.08	0.08	0.08	0.13	0.08	35.08M
November 03, 2026	0.11	0.09	0.09	0.11	0.08	16.5M
November 02, 2026	0.16	0.11	0.11	0.28	0.09	43.04M
October 30, 2026	0.9	0.66	0.66	0.9	0.58	3.5M
October 29, 2026	0.81	0.88	0.88	0.99	0.78	6.63M
October 28, 2026	0.46	0.83	0.83	0.91	0.46	53.8M
October 27, 2026	0.45	0.48	0.48	0.48	0.43	986,007
October 26, 2026	0.48	0.48	0.48	0.49	0.44	1.36M
October 23, 2026	0.54	0.52	0.52	0.56	0.44	1.96M
October 22, 2026	0.44	0.55	0.55	0.55	0.42	7.41M
October 21, 2026	0.36	0.42	0.42	0.43	0.36	1.55M
October 20, 2026	0.34	0.36	0.36	0.39	0.34	761,529
October 19, 2026	0.4	0.35	0.35	0.4	0.33	1.25M
October 16, 2026	0.35	0.39	0.39	0.4	0.33	2.69M
October 15, 2026	0.31	0.35	0.35	0.35	0.31	1.32M
October 14, 2026	0.41	0.32	0.32	0.43	0.32	1.95M
October 13, 2026	0.49	0.43	0.43	0.5	0.4	1.75M
October 12, 2026	0.59	0.51	0.51	0.6	0.5	892,658
October 09, 2026	0.6	0.61	0.61	0.63	0.57	962,002
October 08, 2026	0.63	0.6	0.6	0.64	0.6	870,224
October 07, 2026	0.65	0.65	0.65	0.69	0.63	737,955
October 06, 2026	0.69	0.65	0.65	0.72	0.64	1.18M
October 05, 2026	0.8	0.67	0.67	0.8	0.63	1.98M
October 02, 2026	0.86	0.8	0.8	0.89	0.75	2.34M
October 01, 2026	1.19	0.87	0.87	1.2	0.85	2.63M
September 30, 2026	1.26	1.22	1.22	1.27	1.18	1.75M
September 29, 2026	1.62	1.21	1.21	1.63	1.2	1.86M
September 28, 2026	1.59	1.62	1.62	1.66	1.54	326,527
September 25, 2026	1.73	1.62	1.62	1.77	1.57	1.47M
September 24, 2026	1.73	1.73	1.73	1.77	1.71	677,241
September 23, 2026	1.81	1.75	1.75	1.84	1.66	957,447
September 22, 2026	1.86	1.82	1.82	1.9	1.78	986,716
September 21, 2026	1.81	1.86	1.86	1.92	1.79	1.62M
September 18, 2026	1.77	1.88	1.88	1.89	1.67	1.9M
September 17, 2026	1.75	1.79	1.79	1.85	1.66	1.09M
September 16, 2026	1.54	1.7	1.7	1.72	1.54	1.35M
September 15, 2026	1.59	1.54	1.54	1.7	1.53	1.33M
September 11, 2026	1.5	1.61	1.61	1.61	1.24	6.73M
September 10, 2026	1.68	1.62	1.62	1.68	1.6	798,386
September 09, 2026	1.72	1.69	1.69	1.75	1.65	771,858
September 08, 2026	1.77	1.72	1.72	1.79	1.7	1.01M
September 04, 2026	1.77	1.79	1.79	1.84	1.76	577,292
September 03, 2026	1.78	1.77	1.77	1.81	1.72	0
September 02, 2026	1.9	1.79	1.79	1.94	1.73	1.3M
September 01, 2026	2.02	1.85	1.85	2.07	1.84	1.6M
August 31, 2026	1.91	2.06	2.06	2.14	1.79	2.03M
August 28, 2026	1.98	1.87	1.87	1.99	1.86	823,206
August 27, 2026	1.95	1.94	1.94	2.06	1.94	1.1M
August 26, 2026	1.92	1.96	1.96	1.99	1.86	753,601
August 25, 2026	1.87	1.92	1.92	1.92	1.87	0
August 24, 2026	1.95	1.86	1.86	1.96	1.83	840,490
August 21, 2026	1.85	1.96	1.96	1.97	1.82	873,614
August 20, 2026	2	1.82	1.82	2	1.82	859,990
August 19, 2026	1.94	2	2	2.01	1.94	0
August 18, 2026	1.88	1.93	1.93	1.96	1.82	0
August 17, 2026	2.02	1.81	1.81	2.03	1.79	1.39M