Spero Therapeutics, Inc. (SPRO) NASDAQ

Currency In USD

SPRO Historical Return

If you invested $1000 in Spero Therapeutics, Inc. (SPRO) since IPO date, it would be worth $106.09 as of August 23, 2026, based on a reinvested dividends scenario. Over the same period, a $1000 investment made 5 years ago would be worth $73.98, while $1000 invested 1 year ago would be worth $659.46. This corresponds to total returns of -89.39%, -92.6%, -34.05%, respectively, with annualized returns of -22.48%, -40.58%, -34.05%.

Custom investment amounts or purchase dates can also be explored using the Stoculator calculator. Past performance does not guarantee future results.

SPRO Historical Data

Date Range:

Date	Open	Close	Adj Close	High	Low	Volume
August 21, 2026	1.22	1.22	1.22	1.25	1.21	359,138
August 20, 2026	1.22	1.21	1.21	1.27	1.2	557,879
August 19, 2026	1.23	1.23	1.23	1.24	1.19	0
August 18, 2026	1.2	1.2	1.2	1.2	1.18	0
August 17, 2026	1.21	1.19	1.19	1.24	1.19	299,010
August 14, 2026	1.26	1.23	1.23	1.26	1.19	744,543
August 13, 2026	1.19	1.24	1.24	1.3	1.19	0
August 12, 2026	1.19	1.19	1.19	1.19	1.19	0
August 11, 2026	1.24	1.23	1.23	1.24	1.21	0
August 10, 2026	1.25	1.23	1.23	1.28	1.23	350,798
August 07, 2026	1.27	1.26	1.26	1.28	1.24	0
August 06, 2026	1.26	1.27	1.27	1.27	1.23	972,468
August 05, 2026	1.25	1.26	1.26	1.28	1.21	574,336
August 04, 2026	1.15	1.23	1.23	1.25	1.15	751,966
August 03, 2026	1.19	1.15	1.15	1.22	1.13	1.37M
July 31, 2026	1.2	1.17	1.17	1.21	1.17	811,649
July 30, 2026	1.2	1.2	1.2	1.22	1.18	486,387
July 29, 2026	1.2	1.19	1.19	1.21	1.16	1.06M
July 28, 2026	1.18	1.2	1.2	1.28	1.15	1.6M
July 27, 2026	1.2	1.18	1.18	1.23	1.16	1.35M
July 23, 2026	1.28	1.16	1.16	1.28	1.1	3.72M
July 22, 2026	1.38	1.27	1.27	1.41	1.25	1.99M
July 21, 2026	1.39	1.38	1.38	1.44	1.37	2.17M
July 20, 2026	1.57	1.44	1.44	1.57	1.41	1.71M
July 17, 2026	1.52	1.58	1.58	1.64	1.5	1.25M
July 16, 2026	1.68	1.57	1.57	1.69	1.52	2.61M
July 15, 2026	1.71	1.7	1.7	1.71	1.63	1.41M
July 14, 2026	2.17	1.7	1.7	2.34	1.67	11.21M
July 13, 2026	2.11	2.18	2.18	2.19	2.07	703,476
July 10, 2026	2.12	2.1	2.1	2.16	2.05	480,934
July 09, 2026	2.19	2.12	2.12	2.19	2.12	369,166
July 08, 2026	2.14	2.17	2.17	2.23	2.13	303,907
July 07, 2026	2.16	2.16	2.16	2.19	2.12	877,693
July 06, 2026	2.17	2.19	2.19	2.21	2.15	355,231
July 02, 2026	2.23	2.2	2.2	2.28	2.15	629,507
July 01, 2026	2.21	2.22	2.22	2.27	2.21	397,474
June 30, 2026	2.26	2.21	2.21	2.29	2.2	433,558
June 29, 2026	2.26	2.26	2.26	2.33	2.25	517,549
June 26, 2026	2.03	2.26	2.26	2.33	2.01	2.22M
June 25, 2026	2.12	2.02	2.02	2.13	2.02	1.14M
June 24, 2026	2.15	2.1	2.1	2.23	2.1	887,736
June 23, 2026	2.16	2.15	2.15	2.23	2.15	605,520
June 22, 2026	2.28	2.21	2.21	2.36	2.16	2.23M
June 18, 2026	2.51	2.28	2.28	2.51	2.15	7.15M
June 17, 2026	2.87	2.11	2.11	3.05	1.95	11.04M
June 16, 2026	2.94	2.77	2.77	2.98	2.75	1.43M
June 15, 2026	2.93	2.91	2.91	2.97	2.85	932,530
June 12, 2026	2.72	2.85	2.85	2.85	2.7	623,660
June 11, 2026	2.55	2.7	2.7	2.76	2.48	1.16M
June 10, 2026	2.62	2.54	2.54	2.64	2.51	758,307
June 09, 2026	2.78	2.57	2.57	2.81	2.52	1.13M
June 08, 2026	2.84	2.74	2.74	2.87	2.73	647,636
June 05, 2026	3	2.82	2.82	3	2.76	0
June 04, 2026	2.79	2.98	2.98	3.07	2.78	1.02M
June 03, 2026	2.85	2.8	2.8	2.87	2.77	770,220
June 02, 2026	2.81	2.83	2.83	2.87	2.76	605,758
June 01, 2026	2.83	2.83	2.83	2.89	2.79	646,187
May 29, 2026	2.92	2.83	2.83	2.92	2.75	1.34M
May 28, 2026	2.93	2.9	2.9	3	2.9	790,854
May 27, 2026	2.86	2.93	2.93	3.08	2.81	1.77M