If you invested $1000 in Upstream Bio, Inc. (UPB) since IPO date, it would be worth $316.82 as of August 23, 2026, based on a reinvested dividends scenario. Over the same period, a $1000 investment made 6 months ago would be worth $869.08, while $1000 invested 3 months ago would be worth $848.96. This corresponds to total returns of -68.32%, -13.09%, -15.1%, respectively, with annualized returns of -45.99%, -13.09%, -15.1%.
Custom investment amounts or purchase dates can also be explored using the Stoculator calculator. Past performance does not guarantee future results.
Date Range:
| Date | Open | Close | Adj Close | High | Low | Volume |
|---|---|---|---|---|---|---|
| August 21, 2026 | 6.91 | 6.97 | 6.97 | 7.01 | 6.85 | 434,240 |
| August 20, 2026 | 7.48 | 6.85 | 6.85 | 7.56 | 6.75 | 592,928 |
| August 19, 2026 | 7.04 | 7.52 | 7.52 | 7.52 | 6.93 | 0 |
| August 18, 2026 | 7.28 | 6.85 | 6.85 | 7.44 | 6.73 | 461,648 |
| August 17, 2026 | 7.02 | 7.14 | 7.14 | 7.19 | 6.86 | 852,439 |
| August 14, 2026 | 6.95 | 7.07 | 7.07 | 7.14 | 6.8 | 688,248 |
| August 13, 2026 | 7.02 | 6.91 | 6.91 | 7.04 | 6.87 | 378,828 |
| August 12, 2026 | 7 | 6.91 | 6.91 | 7.25 | 6.84 | 0 |
| August 11, 2026 | 7.48 | 7.09 | 7.09 | 7.7 | 7.01 | 0 |
| August 10, 2026 | 7.32 | 7.44 | 7.44 | 7.62 | 7.2 | 869,590 |
| August 07, 2026 | 6.94 | 7.25 | 7.25 | 7.26 | 6.89 | 621,836 |
| August 06, 2026 | 6.75 | 6.87 | 6.87 | 7.17 | 6.66 | 427,171 |
| August 05, 2026 | 6.77 | 6.74 | 6.74 | 6.88 | 6.58 | 917,141 |
| August 04, 2026 | 6.4 | 6.79 | 6.79 | 6.92 | 6.4 | 1.36M |
| August 03, 2026 | 6.24 | 6.42 | 6.42 | 6.43 | 6.18 | 748,448 |
| July 31, 2026 | 6.58 | 6.31 | 6.31 | 6.69 | 6.29 | 297,713 |
| July 30, 2026 | 6.35 | 6.57 | 6.57 | 6.67 | 6.29 | 320,622 |
| July 29, 2026 | 6.39 | 6.41 | 6.41 | 6.48 | 6.21 | 702,776 |
| July 28, 2026 | 6.4 | 6.4 | 6.4 | 6.54 | 6.09 | 433,233 |
| July 27, 2026 | 6.47 | 6.4 | 6.4 | 6.6 | 6.26 | 459,476 |
| July 24, 2026 | 6.4 | 6.41 | 6.41 | 6.61 | 6.16 | 626,354 |
| July 23, 2026 | 6.46 | 6.4 | 6.4 | 6.59 | 6.32 | 625,610 |
| July 22, 2026 | 6.95 | 6.59 | 6.59 | 6.99 | 6.47 | 704,488 |
| July 21, 2026 | 6.92 | 6.98 | 6.98 | 7.08 | 6.86 | 340,978 |
| July 20, 2026 | 6.99 | 6.98 | 6.98 | 7.15 | 6.8 | 457,968 |
| July 17, 2026 | 7.08 | 7.01 | 7.01 | 7.3 | 6.9 | 378,032 |
| July 16, 2026 | 7.24 | 7.23 | 7.23 | 7.34 | 6.98 | 561,160 |
| July 15, 2026 | 7.12 | 7.27 | 7.27 | 7.32 | 7.08 | 320,948 |
| July 14, 2026 | 7.28 | 7.14 | 7.14 | 7.34 | 7 | 344,692 |
| July 13, 2026 | 7.47 | 7.28 | 7.28 | 7.53 | 7.02 | 266,131 |
| July 10, 2026 | 7.81 | 7.53 | 7.53 | 7.81 | 7.28 | 341,696 |
| July 09, 2026 | 7.98 | 7.81 | 7.81 | 8 | 7.57 | 467,530 |
| July 08, 2026 | 7.73 | 7.98 | 7.98 | 8 | 7.53 | 635,108 |
| July 07, 2026 | 7.48 | 7.86 | 7.86 | 8 | 7.32 | 726,025 |
| July 06, 2026 | 7.5 | 7.4 | 7.4 | 7.59 | 7.34 | 357,006 |
| July 02, 2026 | 7.31 | 7.51 | 7.51 | 7.72 | 7.16 | 363,212 |
| July 01, 2026 | 6.9 | 7.28 | 7.28 | 7.42 | 6.81 | 560,981 |
| June 30, 2026 | 6.94 | 6.92 | 6.92 | 7.38 | 6.88 | 557,817 |
| June 29, 2026 | 6.77 | 6.93 | 6.93 | 7 | 6.56 | 662,668 |
| June 26, 2026 | 6.36 | 6.75 | 6.75 | 6.78 | 6.35 | 1.31M |
| June 25, 2026 | 6.32 | 6.36 | 6.36 | 6.57 | 6.28 | 469,883 |
| June 24, 2026 | 6.35 | 6.35 | 6.35 | 6.71 | 6.32 | 654,555 |
| June 23, 2026 | 6.26 | 6.32 | 6.32 | 6.54 | 6.24 | 623,889 |
| June 22, 2026 | 6.33 | 6.3 | 6.3 | 6.6 | 6.25 | 849,212 |
| June 18, 2026 | 6.26 | 6.25 | 6.25 | 6.52 | 6.15 | 828,997 |
| June 17, 2026 | 5.94 | 6.15 | 6.15 | 6.33 | 5.88 | 839,681 |
| June 16, 2026 | 6.1 | 5.92 | 5.92 | 6.19 | 5.86 | 519,872 |
| June 15, 2026 | 6.19 | 6.1 | 6.1 | 6.28 | 6.01 | 681,421 |
| June 12, 2026 | 6.03 | 6.1 | 6.1 | 6.47 | 5.85 | 1.43M |
| June 11, 2026 | 6.28 | 6.38 | 6.38 | 6.4 | 6.11 | 833,080 |
| June 10, 2026 | 6.64 | 6.28 | 6.28 | 6.8 | 6.25 | 450,140 |
| June 09, 2026 | 6.53 | 6.69 | 6.69 | 6.78 | 6.42 | 500,531 |
| June 08, 2026 | 7.16 | 6.45 | 6.45 | 7.16 | 6.41 | 783,876 |
| June 05, 2026 | 7.39 | 7.05 | 7.05 | 7.45 | 6.98 | 0 |
| June 04, 2026 | 7.68 | 7.43 | 7.43 | 7.78 | 7.3 | 688,030 |
| June 03, 2026 | 7.52 | 7.63 | 7.63 | 7.86 | 7.41 | 665,302 |
| June 02, 2026 | 7.96 | 7.25 | 7.25 | 7.96 | 7.19 | 632,056 |
| June 01, 2026 | 8.33 | 8.08 | 8.08 | 8.64 | 7.99 | 595,030 |
| May 29, 2026 | 8.31 | 8.36 | 8.36 | 8.5 | 8.16 | 498,901 |
| May 28, 2026 | 8.24 | 8.32 | 8.32 | 8.38 | 8.13 | 320,803 |