If you invested $1000 in Upstream Bio, Inc. (UPB) since IPO date, it would be worth $328.64 as of July 17, 2026, based on a reinvested dividends scenario. Over the same period, a $1000 investment made 6 months ago would be worth $233.23, while $1000 invested 3 months ago would be worth $723.72. This corresponds to total returns of -67.14%, -76.68%, -27.63%, respectively, with annualized returns of -46.78%, -76.68%, -27.63%.
Custom investment amounts or purchase dates can also be explored using the Stoculator calculator. Past performance does not guarantee future results.
Date Range:
| Date | Open | Close | Adj Close | High | Low | Volume |
|---|---|---|---|---|---|---|
| July 16, 2026 | 7.24 | 7.23 | 7.23 | 7.34 | 6.98 | 561,160 |
| July 15, 2026 | 7.12 | 7.27 | 7.27 | 7.32 | 7.08 | 320,948 |
| July 14, 2026 | 7.28 | 7.14 | 7.14 | 7.34 | 7 | 344,692 |
| July 13, 2026 | 7.47 | 7.28 | 7.28 | 7.53 | 7.02 | 266,131 |
| July 10, 2026 | 7.81 | 7.53 | 7.53 | 7.81 | 7.28 | 341,696 |
| July 09, 2026 | 7.98 | 7.81 | 7.81 | 8 | 7.57 | 467,530 |
| July 08, 2026 | 7.73 | 7.98 | 7.98 | 8 | 7.53 | 635,108 |
| July 07, 2026 | 7.48 | 7.86 | 7.86 | 8 | 7.32 | 726,025 |
| July 06, 2026 | 7.5 | 7.4 | 7.4 | 7.59 | 7.34 | 357,006 |
| July 02, 2026 | 7.31 | 7.51 | 7.51 | 7.72 | 7.16 | 363,212 |
| July 01, 2026 | 6.9 | 7.28 | 7.28 | 7.42 | 6.81 | 560,981 |
| June 30, 2026 | 6.94 | 6.92 | 6.92 | 7.38 | 6.88 | 557,817 |
| June 29, 2026 | 6.77 | 6.93 | 6.93 | 7 | 6.56 | 662,668 |
| June 26, 2026 | 6.36 | 6.75 | 6.75 | 6.78 | 6.35 | 1.31M |
| June 25, 2026 | 6.32 | 6.36 | 6.36 | 6.57 | 6.28 | 469,883 |
| June 24, 2026 | 6.35 | 6.35 | 6.35 | 6.71 | 6.32 | 654,555 |
| June 23, 2026 | 6.26 | 6.32 | 6.32 | 6.54 | 6.24 | 623,889 |
| June 22, 2026 | 6.33 | 6.3 | 6.3 | 6.6 | 6.25 | 849,212 |
| June 18, 2026 | 6.26 | 6.25 | 6.25 | 6.52 | 6.15 | 828,997 |
| June 17, 2026 | 5.94 | 6.15 | 6.15 | 6.33 | 5.88 | 839,681 |
| June 16, 2026 | 6.1 | 5.92 | 5.92 | 6.19 | 5.86 | 519,872 |
| June 15, 2026 | 6.19 | 6.1 | 6.1 | 6.28 | 6.01 | 681,421 |
| June 12, 2026 | 6.03 | 6.1 | 6.1 | 6.47 | 5.85 | 1.43M |
| June 11, 2026 | 6.28 | 6.38 | 6.38 | 6.4 | 6.11 | 833,080 |
| June 10, 2026 | 6.64 | 6.28 | 6.28 | 6.8 | 6.25 | 450,140 |
| June 09, 2026 | 6.53 | 6.69 | 6.69 | 6.78 | 6.42 | 500,531 |
| June 08, 2026 | 7.16 | 6.45 | 6.45 | 7.16 | 6.41 | 783,876 |
| June 05, 2026 | 7.39 | 7.05 | 7.05 | 7.45 | 6.98 | 0 |
| June 04, 2026 | 7.68 | 7.43 | 7.43 | 7.78 | 7.3 | 688,030 |
| June 03, 2026 | 7.52 | 7.63 | 7.63 | 7.86 | 7.41 | 665,302 |
| June 02, 2026 | 7.96 | 7.25 | 7.25 | 7.96 | 7.19 | 632,056 |
| June 01, 2026 | 8.33 | 8.08 | 8.08 | 8.64 | 7.99 | 595,030 |
| May 29, 2026 | 8.31 | 8.36 | 8.36 | 8.5 | 8.16 | 498,901 |
| May 28, 2026 | 8.24 | 8.32 | 8.32 | 8.38 | 8.13 | 320,803 |
| May 27, 2026 | 8.19 | 8.26 | 8.26 | 8.55 | 8.19 | 420,395 |
| May 26, 2026 | 8.44 | 8.21 | 8.21 | 8.45 | 8.11 | 593,003 |
| May 22, 2026 | 8.47 | 8.37 | 8.37 | 8.69 | 8.33 | 354,422 |
| May 21, 2026 | 8.26 | 8.46 | 8.46 | 8.6 | 8.25 | 591,324 |
| May 20, 2026 | 8.02 | 8.41 | 8.41 | 8.56 | 7.99 | 593,025 |
| May 19, 2026 | 8.42 | 8.03 | 8.03 | 8.64 | 8.02 | 982,478 |
| May 18, 2026 | 8.97 | 8.51 | 8.51 | 9.13 | 8.12 | 511,282 |
| May 15, 2026 | 8.59 | 9.09 | 9.09 | 9.14 | 8.55 | 979,800 |
| May 14, 2026 | 9.45 | 8.79 | 8.79 | 9.52 | 8.51 | 568,491 |
| May 13, 2026 | 8.96 | 9.36 | 9.36 | 9.46 | 8.8 | 815,500 |
| May 12, 2026 | 8.93 | 8.95 | 8.95 | 9.14 | 8.83 | 467,445 |
| May 11, 2026 | 9.2 | 9.11 | 9.11 | 9.6 | 9.05 | 377,652 |
| May 08, 2026 | 8.88 | 9.09 | 9.09 | 9.35 | 8.8 | 456,043 |
| May 07, 2026 | 9.14 | 8.99 | 8.99 | 9.14 | 8.69 | 272,835 |
| May 06, 2026 | 9.16 | 9.19 | 9.19 | 9.29 | 8.98 | 409,160 |
| May 05, 2026 | 9.31 | 9.12 | 9.12 | 9.5 | 8.88 | 262,659 |
| May 04, 2026 | 9.34 | 9.31 | 9.31 | 9.56 | 9.16 | 288,623 |
| May 01, 2026 | 9.25 | 9.4 | 9.4 | 9.41 | 9.12 | 489,694 |
| April 30, 2026 | 9.2 | 9.18 | 9.18 | 9.3 | 9.06 | 394,953 |
| April 29, 2026 | 9.32 | 9.19 | 9.19 | 9.37 | 8.97 | 415,823 |
| April 28, 2026 | 9.32 | 9.51 | 9.51 | 9.65 | 9.28 | 462,242 |
| April 27, 2026 | 9.22 | 9.29 | 9.29 | 9.64 | 9.15 | 664,739 |
| April 24, 2026 | 9.47 | 9.3 | 9.3 | 9.63 | 9.21 | 558,825 |
| April 23, 2026 | 9.62 | 9.6 | 9.6 | 9.72 | 9.38 | 427,993 |
| April 22, 2026 | 9.31 | 9.64 | 9.64 | 9.71 | 9.06 | 624,770 |
| April 21, 2026 | 10.01 | 9.26 | 9.26 | 10.05 | 9.22 | 526,277 |