BioNTech SE (BNTX) NASDAQ

Currency In USD

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BioNTech SE

Address

An der Goldgrube 12

Mainz, RP 55131

Germany

Phone

49 6131 9084 0

Sector

Healthcare

Industry

Biotechnology

Employees

7807

First IPO Date

October 10, 2019

Key Executives

NameTitlePayYear Born
Ugur SahinCo-Founder, Chief Executive Officer & Chair of the Management Board1.19M1965
Ozlem TureciCo-Founder, Chief Medical Officer & Member of Management Board952,5751967
Sierk PöttingMD, Chief Operating Officer & Member of Management Board983,1581973
James Timothy Patrick RyanChief Legal & Business Officer and Member of the Management Board1.01M1975
Annemarie HanekampChief Commercial Officer & Member of Management Board1.02M1980
Ramon Zapata-GomezChief Financial Officer & Member of Management Board1.16M1974
Jasmina AlatovicVice President Corporate Communications0N/A
Douglas MaffeiVice President of Strategy & Investor Relations0N/A
Kylie JimenezChief People Officer & Member of Management Board01976
Lisa BirringerSenior Vice President of Global Financial Reporting & Accounting0N/A
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Description

BioNTech SE, a biotechnology firm, specializes in the creation and marketing of immune-based treatments for malignancies and various infectious diseases. A significant part of its oncology pipeline includes the FixVac cancer vaccine program, which features several candidates in different phases of clinical development: BNT111 is in Phase 2 for advanced melanoma. BNT112 has reached Phase 1/2a for prostate cancer. BNT113 is undergoing Phase 2 investigation for HPV-positive head and neck cancers. BNT114 is in Phase 1 for triple-negative breast cancer. BNT115 is also in Phase 1, targeting ovarian cancer. BNT116 is a preclinical candidate for non-small cell lung cancer. The company also pioneers personalized therapies that target neoantigens, such as Autogene cevumeran (BNT122), which is in Phase 2 for first-line melanoma and Phase 1a/1b for a range of solid tumors. Furthermore, its pipeline includes an mRNA-based intratumoral immunotherapy, SAR441000, currently in Phase 1 for solid tumors, as well as BNT141 and BNT142, also in Phase 1 for multiple solid tumors. BioNTech's portfolio extends to RiboCytokine therapies (BNT151, BNT152, and BNT153) aimed at solid tumors, and cutting-edge chimeric antigen receptor T-cell (CAR T-cell) immunotherapies like BNT211 for various solid tumors and BNT221 for other types of cancer. Immune checkpoint modulators, specifically GEN1046 and GEN1042, are also under Phase 1/2 clinical investigation for solid tumors. Beyond these, the firm is developing BNT321, an IgG1 monoclonal antibody in Phase 2 for pancreatic cancer, and BNT411, a small molecule immunomodulator candidate for solid tumors. Its broader scope encompasses preventative vaccines for illnesses like COVID-19 and Influenza, additional immunotherapies for infectious diseases, and protein replacement therapies designed for rare conditions. To advance its extensive pipeline, BioNTech has forged strategic partnerships with major pharmaceutical and biotechnology firms, including Genentech, Sanofi S.A., Genmab A/S, Pfizer Inc., Shanghai Fosun Pharmaceutical (Group) Co., Ltd., and Regeneron Pharmaceuticals, Inc. Established in 2008, BioNTech SE maintains its principal operations in Mainz, Germany.

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