Address
3 Lochside Way
Edinburgh, EH12 9DT
United Kingdom of Great Britain and Northern Ireland (the)
Phone
44 13 1357 1111
Website
Sector
Healthcare
Industry
Biotechnology
Employees
20
First IPO Date
September 28, 2017
| Name | Title | Pay | Year Born |
| Hugh Stephen Griffith | Founder, Chief Executive Officer & Executive Director | 1.44M | 1968 |
| Jeffrey D. Bloss | Chief Medical Officer | 104,566 | 1958 |
| Ian Webster | Chief Financial Officer | 0 | 1981 |
| Theresa Bruce | Chief Operating Officer | 0 | 1965 |
| David Harrison | Head of Translational Medicine & Studies | 0 | 1960 |
| Stuart Grant | Senior Vice President of Regulatory Affairs | 0 | N/A |
| Gordon Kennovin | Senior Vice President of CMC & Development | 0 | N/A |
| Martin Quinn | Company Secretary | 0 | N/A |
NuCana plc is a clinical-stage biopharmaceutical firm dedicated to pioneering advanced therapies for oncology. Its innovative product pipeline is underpinned by a proprietary ProTide technology platform. Among its key drug candidates, Acelarin is progressing through multiple clinical evaluations: a Phase I study for advanced solid tumors, Phase Ib trials for both recurrent ovarian cancer and biliary tract cancer, a Phase II trial targeting platinum-resistant ovarian cancer, and a pivotal Phase III trial for pancreatic cancer. NuCana is also developing NUC-3373, a ProTide derivative of 5-fluorouracil’s active anti-cancer metabolite. This compound is currently in a Phase I study for advanced solid tumors and a Phase Ib/2 trial for advanced colorectal cancer. Additionally, NUC-7738, a nucleoside analog, is undergoing Phase 1/2 clinical assessment for both advanced solid and hematological malignancies. To support its ProTide technology development, the company maintains research, collaboration, and licensing agreements with Cardiff University and University College Cardiff Consultants Ltd., covering the design, synthesis, characterization, and assessment of these compounds. Further collaborative and licensing arrangements are in place with Cardiff ProTides Ltd. Established in 1997, the company operated as NuCana BioMed Limited before rebranding to NuCana plc in August 2017. Its corporate headquarters are located in Edinburgh, United Kingdom.