Address
One Commerce Square
Philadelphia, PA 19103
United States of America (the)
Phone
267 866 0311
Website
Sector
Healthcare
Industry
Biotechnology
Employees
60
First IPO Date
February 28, 2020
| Name | Title | Pay | Year Born |
| William Chou | President, Chief Executive Officer & Director | 1.01M | 1973 |
| Kathleen Borthwick | Senior Vice President, Chief Financial Officer, Principal Financial Officer & Principal Accounting Officer | 649,379 | 1977 |
| Sue Browne | Chief Scientific Officer | 0 | N/A |
| Karl Whitney | Senior Vice President of Global Regulatory Affairs | 0 | N/A |
| Eden Fucci | Senior Vice President of Technical Operations | 0 | N/A |
| Stuart Henderson | Chief Business Officer | 0 | N/A |
Passage Bio, Inc. is a biopharmaceutical company dedicated to pioneering genetic therapies for conditions affecting the central nervous system. Their advanced pipeline includes PBGM01, designed to treat infantile GM1 gangliosidosis by utilizing a proprietary AAVhu68 capsid to deliver a functional GLB1 gene, which codes for the lysosomal acid beta-galactosidase enzyme, to both the brain and peripheral tissues. Another key program, PBFT02, employs an AAV1 capsid to introduce a functional granulin (GRN) gene, encoding progranulin (PGRN), to the brain as a treatment for FTD-GRN. Additionally, PBKR03 is under development for infantile Krabbe disease, leveraging a proprietary AAVhu68 capsid to deliver a functional GALC gene, responsible for producing the hydrolytic enzyme galactosylceramidase, to the brain and surrounding tissues. The company's portfolio also features PBML04 for metachromatic leukodystrophy, PBAL05 for amyotrophic lateral sclerosis, and PBCM06 for Charcot-Marie-Tooth Type 2A. Passage Bio maintains a significant research collaboration with the Trustees of the University of Pennsylvania's Gene Therapy Program, alongside a development services and clinical supply agreement with Catalent Maryland, Inc. Established in 2017, the company's headquarters are located in Philadelphia, Pennsylvania.