Silence Therapeutics plc (SLN) NASDAQ

5.58

+0.0957(+1.74%)

Updated at August 18 03:18PM

Currency In USD

Silence Therapeutics plc

Address

72 Hammersmith Road

London, W14 8TH

United Kingdom of Great Britain and Northern Ireland

Phone

44 20 3457 6900

Sector

Healthcare

Industry

Biotechnology

Employees

116

First IPO Date

September 08, 2020

Key Executives

NameTitlePayYear Born
Mr. Craig A. Tooman M.B.A.President, Chief Executive Officer & Executive Director1M1965
Dr. Steven J. Romano M.D.Executive Vice President and Chief Research & Development Officer662,4691959
Ms. Rhonda L. HellumsExecutive Vice President, Chief Financial Officer & Secretary677,1301972
Dr. Marie Wikstrom Lindholm Ph.D.Chief Scientific Officer0N/A
Dr. Barbara A. Ruskin J.D., Ph.D.Senior Vice President and Chief Intellectual Property & Innovation Officer01961
Mr. J.P. GabrielChief Technical Operations Officer0N/A
Dr. Eric Floyd M.B.A., M.S., Ph.D.Senior Vice President of Regulatory Affairs & Quality Assurance01964
Ms. Gem Gokmen HopkinsHead of IR & Corporate Communications0N/A
Mr. Curtis Rambaran M.D.Chief Medical Officer0N/A
Ms. Gianine EspositoChief Human Resources Officer0N/A

Description

Silence Therapeutics plc, a biotechnology company, focuses on the discovery and development of novel ribonucleic acid (RNA) therapeutics in hematology, cardiovascular, and other rare and metabolic indications. The company's platform includes mRNAi GalNAc Oligonucleotide Discovery platform designed to accurately target specific disease-associated genes in the liver. It designs short interfering RNA molecules to harness the body's natural mechanism of RNA interference, and degrading messenger RNA molecules that encode specific targeted disease-associated proteins in a cell. The company is developing various product candidates, including SLN360, which is Phase I clinical trials for the treatment of cardiovascular disease with high lipoprotein; SLN124 that is in Phase I clinical trials for the treatment of non-transfusion dependent thalassemia, and Phase I clinical trials for the treatment of myelodysplastic syndrome; and SLN124 for the treatment of polycythemia vera. It has collaboration agreements with AstraZeneca PLC to discover, develop, and commercialize small interfering RNA therapeutics for the treatment of cardiovascular, renal, metabolic, and respiratory diseases; and Mallinckrodt Pharma IP Trading DAC to develop and commercialize RNAi drug targets designed to silence the complement cascade in complement-mediated disorders. The company also has a collaboration with Hansoh Pharmaceutical Group Company Limited to develop siRNAs for three undisclosed targets leveraging Silence's mRNAi GOLD platform. The company was formerly known as SR Pharma plc and changed its name to Silence Therapeutics plc in May 2007. Silence Therapeutics plc is headquartered in London, the United Kingdom.